Treatment of 26 Cases of Chronic Severe Hepatitis with Modified Yinchen Zhufu Decoction / 国际中医中药杂志

ABSTRACT

Objective To observe the effect of treating chronic severe hepatitis modified Yinchen Zhufu Decoction.Methods 46 chronic severe hepatitis patients (belonging to Ymhuang syndrome in TCM) were randomly recruited in to a treatment group (26 cases) and a control group (20 cases). Indexes as symptoms, signs, liver functions, prothrombin activity (PTA), prothrombin (ALB) and complications were used for evaluating therapeutic effects. Results After four weeks' treatment, of all 26 cases in the treatment group, 23 cases were effective (occupying 88.5%) and 3 cases were inefficacy (occupying 11.5%); while of all 20 cases in the control group, 11 cases were effective (occupying 55%) and 9 cases were inefficacy (occupying 45%). There was significant difference between the two group in therapeutic effects( P＜0.05 ). TBIL in both groups were decreased after the treatment(P＜ 0.05 ), and the decrease amplitude in the treatment group was much bigger than the control group (P＜0.05). PTA in the treatment group was increased after the treatment (P＜0.05), but this increase amplitude showed no significant difference comparing with the control group (P＞0.05). ALB showed significant difference between the two groups after treatment, with P＜0.05, but complications demonstrated no significant difference between the two groups after treatment, with P＞0.05. Conclusion Modified Yinchen Zhufu Decoction has good therapeutic effects in treating chronic severe hepatitis of yinhuang syndrome.