Relation among abnormal pulse pressure and cardiovascular risk factors, cardiac function in Tibetan adults from Songpan county of Sichuan province in China / 心血管康复医学杂志

ABSTRACT

Objective: To explore relation among abnormal pulse pressure (PP) and cardiovascular risk factors, cardiac function in Tibetan adults through survey on distributive characteristics of PP in Tibetan adults from Songpan county, Sichuan province in China. Methods: An cross-section study was carried out in Songpan county, Sichuan province of China. Questionnaire investigation and Physical examination were performed by multi-phase, stratified, unequal proportional and random cluster sampling to investigate 1015 Tibetan adults aged 18~74 years. Results: In Songpan county the average PP is （45.59±14.22）mmHg ; the incidence rate of abnormal PP was 14.09％（143/1015）. Multifactor linear regression and Logistic regression analysis showed that abnormal PP was positively related with age (OR=1.05, P<0.05) and negatively related with level of high density lipoprotein (OR=-2.69, P<0.05). Compare with normal PP group, systemic vascular resistance [SVR, (1112.61±346.74) kPa/L vs. (1308.27±354.87) kPa/L, t=-4.87] significantly increased, levels of cardiac index [CI, (3.55±1.00) L/min•m2 vs. (3.22±0.54) L/min•m2, t=3.08] and stroke index [SI, (45.68±12.76) ml/m2 vs. (39.45±9.52) ml/m2, t=4.37] significantly decreased in abnormal PP group (P<0.05 all). Conclusion: Abnormal PP is common in Chinese Tibetan adults aged 18~74 years, which associated with cardiovascular risk factors and change of cardiac function. Health management for Tibetan adults with abnormal PP is strongly advocated.