Determination of strychnine and brucine in maqianzi san by RP-HPLC / 中国药学杂志
Chinese Pharmaceutical Journal
;
(24): 167-1998.
Article
in Chinese
| WPRIM
| ID: wpr-598311
ABSTRACT
OBJECTIVE:
To develop a HPLC method for assaying strychnine and brucine in traditional Chinese drug Maqianzi San.METHODS:
With μBondapak C18 (10 μm) column (4 mm×300 mm), MeOH-H2O-HAc-(C2H5)3N(70∶230∶2.4∶0.3) as mobile phase, we set a detector at 254 nm.RESULTS:
Linear range of strychnine and brucine was 0.367 2 μg~0.061 2 μg and 0.945 0 μg~0.157 5 μg respectively. The recovery rate of strychnine and brucine was 100.36% (RSD=1.09%) and 100.01% (RSD=1.46%) respectively.CONCLUSION:
This method provides a simple and feasible way to control the quality of Maqianzi San.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chinese Pharmaceutical Journal
Year:
1998
Type:
Article
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