Clinical value of 1H-MRS and DTI in glioma classification* / 重庆医学

ABSTRACT

Objective To analyze the performance of the glioma in proton magnetic resonance spectroscopy (1H-MRS) and diffu-sion tensor imaging(DTI) ,and to explore the relationship between the characteristics and pathological grade .Methods The 41 ca-ses of glioma patients were divided into two groups according to the World Health Organization (WHO) classification method:the low-level group and the high-level group .The patients underwent conventional magnetic resonance imaging ,DTI and 1H-MRS ex-amination ,and the ipsilateral placeholder district and contralateral reference zones ADC ,FA ,Cho ,NAA and Cr values were meas-ured .Results The difference of ADC and FA values in solid area between the two groups was significant compared with the contra-lateral ones (P< 0 .05) .The difference of ADC and FA value of the gliomas between the two groups was also significant (P<0 .05) .The NAA/Cr and Cho/Cr values in the two groups of glioma tumor was significantly different compared with the contralat-eral ones (P<0 .05) .The NAA/Cr and NAA/Cho values of the gliomas between the two groups were also significantly different (P<0 .05) .Conclusion The performance of glioma in 1H-MRS and DTI between the two groups showed significantly different .