Expression of the tight junction proteins in inflammatory bowel disease / 国际儿科学杂志

ABSTRACT

The changes in tight junction proteins expression have effects on the function of the intestinal barrier.It is an important factor involved in the pathogenesis of inflammatory bowel disease.The levels of expression of tight junction proteins have been detected by different techniques in inflammatory bowel disease.The mechanism which leads to changes of tight junction proteins is still unknown completely.It is helpful to understand the pathogenesis of inflammatory of bowel disease by discussing the mechanism of changes in tight junction proteins.Improving expression of tight junction proteins is one of our strategies to treat inflammatory bowel disease,and some drugs have been identified.