The expression of N-cadherin and vimentin in rectum adenocarcinoma and their clinical value / 重庆医学
Chongqing Medicine
;
(36): 935-936,940, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-598875
ABSTRACT
Objective To observe the expression of neuronal cadherin (N-cadherin) and vimentin in primary rectum adenocarci-noma tissues and their clinical value .Methods 58 cases of primary rectum adenocarcinoma tissues after surgical resection and con-firmed by pathology ,and normal rectum tissues that at lest 5 cm away from the tumor were selected .The immunohistochemical SP method was used to detect the expression of N-cadherin and vimentin and analyzed their correlation .Results In rectum adenocarci-noma tissues ,the positive expression rate of N-cadherin and vimentin[53 .4% (31/58) ,46 .6% (27/58)]were significantly higher than those of in normal rectum mucosa tissues[3 .4% (2/58) ,1 .7% (1/58)] ,(P0 .05) .Conclusion N-cadherin and vim-entin have close relationships with metastasis of rectum adenocarcinoma ,to detect the expressions of N-cadherin and vimentin is of a effective method to judge the metastasis and prognosis of rectum adenocarcinoma .
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Chongqing Medicine
Year:
2014
Type:
Article
Similar
MEDLINE
...
LILACS
LIS