Risk factors for healthcare-associated infections caused by Candida / 中国感染控制杂志

ABSTRACT

Objective To explore the risk factors for healthcare-associated infection (HAI)caused by Candidain a hospital.Methods 64 patients with healthcare-associated(HA)Candidainfection in a hospital between January 201 1 and October 2013 were selected as case group,and 64 patients without HACandidainfection during the same period were as control group,clinical data of two groups of patients were analyzed.Results The mainCandidacau-sing HAI were Candidaalbicans(68. 75% ),followed by Candidatropicalis(15. 62% ),Candidaglabrata (9.38% )andCandidakrusei(6.25% ).The major infection sites were respiratory tract(67.19% ),urinary tract (18.75% )and digestive tract(10.94% ). Univariate analysis showed the risk factors for HA Candidainfection were age,length of hospital stay,diabetes,and malignant tumor and so on;multivariate logistic regression analysis showed that important risk factors for HACandidainfection were age(OR95% CI2.57-33.67),length of hospi-tal stay(OR95% CI2.17-25.37),malignant tumor(OR95% CI1.04-15.23),chemotherapy(OR95% CI1.76-20.63),and use of respirator(OR95% CI4.67-96.37).Conclusion Risk factors for HACandidainfection are complicated,in order to reduce the incidence of HA Candidainfection,risk factors should be considered,and preventive measures according to risk factors should be made.