A Case of Primary Colon Amyloidosis Presenting as Hematochezia / 대한소화기학회지
The Korean Journal of Gastroenterology
;
: 44-47, 2012.
Article
in Korean
| WPRIM
| ID: wpr-59913
ABSTRACT
Amyloidosis is characterized by a deposition of insoluble fibrils in various organs and tissues. Amyloid deposition, in the gastrointestinal track, provokes a dysfunction of the organ, due to an accumulation of fibrils, and causes a variety of clinical symptoms and endoscopic findings. Primary amyloidosis in the gastrointestinal tract is rarely reported in Korea. We experienced a case of recurrent intestinal bleeding, in a 59-year-old female patient with primary amyloidosis. A colonoscopy revealed the presence of multiple large circular ulcers. In the entire colon, diffuse nodular lesions with edema and bleeding were found. A colonoscopic biopsy established the diagnosis of amyloidosis, to the exclusion of other disease components. We concluded that the patient had localized amyloidosis. Though a definitive therapeutic strategy has not been established for localized gastrointestinal amyloidosis, the patient has been successfully treated with a high-dose of steroids and azathioprine.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Steroids
/
Tomography, X-Ray Computed
/
Colonoscopy
/
Colon
/
Gastrointestinal Hemorrhage
/
Amyloidosis
/
Mercaptopurine
/
Antimetabolites
Limits:
Female
/
Humans
Language:
Korean
Journal:
The Korean Journal of Gastroenterology
Year:
2012
Type:
Article
Similar
MEDLINE
...
LILACS
LIS