Healthcare-associated infection in patients with traumatic brain inj ury and cerebrovascular diseases in an intensive care unit / 中国感染控制杂志

ABSTRACT

Objective To analyze the status of healthcare-associated infection(HAI)and characteristics of patho-gens in patients with traumatic brain inj ury and cerebrovascular diseases,and evaluate prevention and control meas-ures.Methods Clinical data of 236 patients with traumatic brain injury and cerebrovascular diseases in a hospital from 2008 to 2010 were analyzed retrospectively.Results A total of 29 patients developed 50 times of HAI,HAI rate was 12.29%,HAI case rate was 21.19%,HAI case rate of respiratory system,urinary system,oral cavity, gastrointestinal tract,skin and soft tissue,and other sites was 46.00%(n=23),30.00%(n=15),8.00%(n=4), 6.00%(n=3),4.00%(n=2),and 6.00%(n=3)respectively.A total of 69 pathogenic strains were detected,per-centage of gram-negative bacteria was 65.22%(n=45),the major were Pseudomonasaeruginosa(n=17),Klebsiel-lapneumoniae(n=12),Escherichiacoli(n=10),and Acinetobacterbaumannii(n=4);percentage of gram-positive bacteria was 30.43%(n=21),the major were Staphylococcusaureus(n=11),Staphylococcusepidermidis (n=7), Streptococcus spp.(n=2);percentage of fungi was 4.35%(n=3).Conclusion HAI in patients with traumatic brain inj ury and cerebrovascular diseases is high,the main infection site is respiratory system,the main pathogens are gram-negative bacteria.Preventive and control measures should be taken accordingly.