Effect of Toddalia Asiatica on Plasma Recalcification Time in Rabbits / 中国药师

ABSTRACT

Objective:To preliminarily study on the procoagulant activity of Toddalia asiatica Lam. Methods:The plasma recal-cification time affected by the water decoction extract, ultrasonic extract and organic solvent extract from T. asiatica were determined to observe the effects of different extracts from T. asiatica on plasma recalcification time of rabbits. Results:The ultrasonic extract of T. asiatica could reduce the plasma recalcification time (P<0. 05), the ethyl acetate and methanol extract could significantly reduce the plasma recalcification time (P <0. 01), while the water decoction extract prolonged the plasma recalcification time (0.01

Conclusion:The ultrasonic extract, ethyl acetate parts and methanol parts of T. asiatica have potential procoagulant activity, while the water decoction extract of T. asiatica shows potential anticoagulant activity.