Meta-analysis of feasibility of ovarian preservation in early youth endometrial cancers / 中国医师杂志

ABSTRACT

Objective To investigate feasibility of ovarian preservation in early youth endometrial cancer (EC).Methods We searched the database.All the calculations and statistical tests were performed with the Revman 5.2 software.The odds risk (OR) of cancer recurrence or death was taken as observation index.Results The experimental group was compared to control group,the risks of relapse and death were similar.The combined OR of all relapse risk was 0.87 with a 95％ of confidence interval (0.44 ～ 1.70).While the combined OR of all death risk was 0.70 with a 95％ of confidence interval (0.42 ～ 1.15).Conclusions The present data show that ovarian preservation in early youth EC is feasible because the treatment can not increase the risks of relapse and death.However,this conclusion needs to be further confirmed with high-quality randomized clinical trials.