Analysis on clinical distribution and drug resistance of 579 strains of Acinetobacter baumannii / 国际检验医学杂志

ABSTRACT

Objective To understand the specimen source of clinical isolated Acinetobacter(A.)baumannii and its department distribution and drug resistance in order to guide the clinical standardized medication for preventing the drug resistance increase. Methods The drug resistance of A.baumannii was monitored by using the unified scheme,materials,methods and criteria (CLSI2010).Results Among 579 strains of A.Baumannii,39 strains(2.2%)were isolated in 2011,187 strains(10.5%)were isola-ted in 2012 and 353 strains(15.4%)were isolated in 2013.In the department distribution,271 strains were isolated from ICU and 104 strains from the department of respiratory medicine.In the positive isolation rates of various specimens,the positive rate was dominated by the sputum specimen(5.55%),followed by wound secretion and pus.The antibacterial susceptibility tests showed that A.baumannii had lowest resistance to cefoperazone/sulbactam(40.1%),which could be used as the drug of first choice.Con-clusion A.baumannii has the higher resistance to many kinds of antibacterial drugs.The drug resistance monitoring of A.bauman-nii should be strengthened in clinc and antibacterial drugs should be selected and used rationally.