Application of two methods in the treatment of esophageal Intraepithelial neoplasia / 重庆医学

ABSTRACT

Objective To compare the effectiveness and safety of endoscopic polycyclic mucosal resection(EMBM)and endo-scopic submucosal dissection(ESD)in the treatment of esophageal intraepithelial neoplasia.Methods 85 cases of esophageal intra-epithelial neoplasia patients,including 45 cases treated by EMBM and 40 cases treated by ESD.To compare the efficacy,complica-tions,operation time,and medical fees of the two treatment methods by analysis of relevant clinical data.Results Once resection rate of the EMBM treatment group was 97.8%(44/45),and 95.0%(38/40)for the ESD treatment group,there is no significant difference between the two groups(P>0.05);Endoscopy of both treated patients in the postoperative 1,3,6,and 12 months showed no recurrence;The complications incidence of bleeding and perforation of the EMBM treated group(8.89%,0)was significantly lower than that of the ESD treated group(35.00%,15.00%),P<0.05;The average operation time of the EMBM treated group [(26.5±14.2)min]was significantly lower than that of the ESD treated group[(65.2±26.1)min],P<0.05;The total cost of hospitalization of the ESD treated group(18 000 yuan)was significantly higher than the EMBM treated group(8 500 yuan),P<0.05.Conclusion Compared with ESD,EMBM has an easier operation,less complications and patient consuming,and it is suitable for application in primary hospitals.