Clinical study on myocardial enzymes,troponin for diagnosing children hand-foot-mouth disease complicating myocarditis / 国际检验医学杂志

ABSTRACT

Objective To study the clinical application value of myocardial enzymes and troponin in children hand-foot-mouth disease complicating myocardial injury.Methods 143 cases of clinically diagnosed children hand-foot-mouth disease were set as the HFMD group,and divided into the normal group (59 cases)and abnormal electrocardiogram group (84 cases)according to the ECG examination results.Contemporaneous 67 healthy infants and young children with physical examination were selected as the control group.The changes of myocardial enzymes and troponin were compared among various groups.The change situation of myocardial enzymes and troponin during acute and convalescent stages in abnormal ECG group were studied.Results The myocardial en-zymes,serum troponin concentration and the abnormal rate had statistical differences between the HFMD abnormal ECG group with the HFMD normal EKG group and the control group (P 0.05);the serum CK,CK-MB cTnT-hs levels had statistical differences between the acute stage and the convalescent stage in the HFMD abnormal EKG group(P 0.05).Conclusion Myocardial injury is more serious complication in children patients with HFMD,clinic should take prevention first,conducting the monitoring of myocardial enzymes and troponin has important clinical significance.