Influence of PCT level on prognosis in patients with acute coronary syndrome / 国际检验医学杂志

ABSTRACT

Objective To study the influence of procalcitonin (PCT)on the prognosis in the patients with acute coronary syn-drome(ACS)to provide the basis for clinic treatment.Methods 210 cases of ACS treated in our hospital from May 2013 to May 2014 were selected and divided into the group A (n=121),B (n=49)and C (n=40)according to their PCT levels,the group APCT≤0.05 ng/mL,the group B0.05 non-ST-elevation myocardial infarction (NSTEMI)or unstable angina (UA),simple-ST-elevation acute myocardial infarction (STEMI),cardiogenic shock (CS)complicating STEMI were compared among 3 groups.Finally,the correlation between PCT level with the incidence of major adverse cardiac events and the mortality rate was analyzed by using COX regression.Results The oc-currence rate of CS in the roup C was significantly higher than that in the group A and B,and the occurrence rate of CS in the group B was significantly higher than that in the group A,the differences were statistical significant (P <0.05 ).The occurrence rate of NSTEMI/UA and STEMI in the group C was significantly lower than that in the group A and B,the difference was also statistical significant (P <0.05);the COX regression analysis revealed that the PCT level was positively correlated with the incidence of major adverse cardiac events and the mortality rate (P <0.05).Conclusion The PCT level is a high-risk factor of ACS and is closely re-lated with the incidence of major adverse cardiac events and the mortality rate.