Application of MLPA for analysis of chromosomal unbalances / 国际检验医学杂志
International Journal of Laboratory Medicine
;
(12): 1336-1337,1340, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-600836
ABSTRACT
Objective To valuate the applicability of multiplex ligation‐dependent probe amplication (MLPA ) for detection of chromosomal unbalance .Methods Aneuploid and subtelomeric MLPA technology were used to analyze 6 samples with chromosom‐al unbalances ,confirmed by karyotype analysis .Results All samples were identified to have abnormal signal of corresponding probes .The extent of unbalances contained subtelomeric region .Conclusion MLPA technology could have important role in diag‐nosis of chromosomal unbalance ,which could complement conventional karyotype analysis .
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
International Journal of Laboratory Medicine
Year:
2015
Type:
Article
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