Clinical value of serum progesterone, β-HCG joint detection in early threatened abortion / 中国生化药物杂志

ABSTRACT

Objective To investigate the clinical value of serum progesterone, β-HCG combined detection in early threatened abortion. Methods According to the result of pregnancy in the hospital, 140 cases of early threatened abortion maternal and were divided into two groups, that threatened abortion group 90 cases( threatened abortion symptoms in early pregnancy but after follow-up miscarriage treatment successful producers).And abortion 50 cases (threatened abortion symptoms in early pregnancy, but after conventional therapy, the miscarriage was failure and termination of pregnancy ).And 90 cases of normal pregnant women were selected as control group in the same period of birth to check in the hospital,and detected in serum progesterone and β-HCG content of three groups of patients, and analyzed.Results Between threatened abortion group and the control group, serum progesterone and β-HCG was no significant difference.West blot results, the value of serum progesterone in abortion group was significantly lower than the other 2 groups, abortion group β-HCG was lower than that of the control group and threatened abortion group, with significant difference ( P12.2ng/mL, maternal pregnancy continued probability was greater than the natural abortion, with significant difference ( P5000 IU/mL, maternal pregnancy continued probability was greater than the natural abortion, with significant difference ( P<0.05 ).Progesterone, β-HCG, progesterone and β-HCG joint detection, joint detection sensitivity ( 87.09%) was higher than progesterone, β-HCG alone detection ( 76.33% and 60.34%) , the difference was statistically significant (P<0.05 ).Progesterone, β-HCG, progesterone joint detection of specific were 85.00%, 100.00% and 90.00%, there were not statistically significant.Conclusions Serum progesterone and β-HCG joint detection for early threatened abortion diagnosis has guiding significance, can improve the accuracy and sensitivity of the test results, which can effectively guide clinical practice.