The clinical effectiveness analysis of early use of low molecular weight heparin and aspirin in the treatment of acute cerebral infarction / 中国基层医药

ABSTRACT

Objective To study the clinical effectiveness analysis of early use of low molecular weight hepa-rin and aspirin in the treatment of acute cerebral infarction.Methods 120 cases with acute cerebral infarction were randomly divided into the observation group and the control group according to a random number table,with 60 cases in each group.The patients of the control group were treated with aspirin,while the patients of the observation group were given low molecular weight heparin on the basis of the control group.Both groups were treated for one month,and the therapeutic effects and adverse reactions of the two groups were compared.Results The total efficiency of the ob-servation group was 96.7%(58 /60),which was significantly higher than the 76.7%(46 /60)of the control group, the difference was statistically significant(χ2 =12.051,P =0.019);The neurological deficits after treatment of the observation group was (16.21 ±2.05 )points,which was significantly lower than (26.04 ±1.03)points of the control group,the difference was statistically significant (t =10.372,P =0.027 ).Conclusion Acute cerebral infarction early use of low molecular weight heparin and aspirin had better clinical efficacy,and it can significantly promote the recovery of neurological function in patients.