Effect of dezocine on the agitations after remifentanil-sevoflurane anaesthesia / 中国医学装备

ABSTRACT

Objective:To analyze the effect of dezocine on the agitations after remifentanil-sevoflurane anaesthesia.Methods: Choose patients received remifentanil sevoflurane anesthesia in our hospital as study object, randomly divided into observation group received Dezocine intervention and control group received saline, compared with agitation score, VAS and BCS score, CRP and inflammatory cytokines level.Results:1)observation group patients’ average score of agitation restlessness and probability after intervention were significantly lower than control group; 2)observation group patients’ BCS and VAS scores after intervention were significantly lower than control group patients; 3)CRP and inflammatory cytokines recovery period of two groups of patients have risen, but observation group were significantly better than control group patients(t=3.950,t=4.739,t=6.493;P<0.05).Conclusion: Dezocine help mitigate wake of remifentanil sevoflurane agitation in patients, reduce pain experience while optimizing factor levels in vivo, with a positive clinical significance.