Causes of false-positive anti-HCV in non-syndromic cleft lip and palate with serum chemiluminescence test / 中国免疫学杂志
Chinese Journal of Immunology
;
(12): 795-797,802, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-601507
ABSTRACT
Objective:
To investigate the causes of false-positive anti-HCV in non-syndromic cleft lip and palate with serum chemiluminescence test.Methods:
We performed a hospital-based,case-control study of 4 050 patients with non-syndromic cleft lip and palate and 8 547 control patients without cleft lip and palate to evaluate associations between positive anti-HCV and non-syndromic cleft lip and palate. CLIA test were used for detect anti-HCV in control group. RIBA and FQ-PCR were used for confirming the result of the positive samples of CLIA test. CLIA test were used for detect anti-HCV in case group until CLIA test was negative. IgG,RF and ANA were used for case-control comparisons.Results:
The detection rate of anti-HCV were higher in the case group than that of control group (P<0. 05). The false-positive rate was 1 percent based on testing of 4 050 patients. These samples were negative after opration 1-19 months. There were no change among IgG, RF and ANA in the false-positivepatients.Conclusion:
False-positive anti-HCV in non-syndromic cleft lip was possible associated with abnormal plasma metabolic product. It can be excluded by track monitoring.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Etiology study
/
Observational study
/
Risk factors
Language:
Chinese
Journal:
Chinese Journal of Immunology
Year:
2015
Type:
Article
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