TAD regimen with melphalan to treat 18 cases of multiple myeloma / 白血病·淋巴瘤
Journal of Leukemia & Lymphoma
;
(12): 351-352,355, 2008.
Article
in Chinese
| WPRIM
| ID: wpr-601772
ABSTRACT
Objective To observe the clinical results of combination therapy for multiple myeloma by arsenic trioxide,melphalan,vitamin C and dexamethasone.Methods 18 cases with multiple myeloma,12 males and 6 females were given the treatment including arsenic trioxide,melphalan,vitamin C and dexamethasone combination therapy;the dosage of arsenic trioxide 10 mg,d1~5,d8~12;vitamin C 1.0 g,d1~5,d8~12;dexamethasone 20 mg,d1~4,d8~11;melphalan 2 mg,tid,d1~12.Complete response(CR),partial response(PR),minimal response(MR),no ehange(NC)were observed.Results The CR werel6.7%(3/18),PR were 77.7%(14/t8),MR were 5.6%(1/18).Conclusion Combinational arsenic trioxide,melphalan,vitamin C and dexamethasone is an effective therapy with less side effects,which can be considered for treating the initial or relapsed or refractory MM.
Full text:
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Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Leukemia & Lymphoma
Year:
2008
Type:
Article
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