Clinicopathological study of 69 cases of secondary myelofibrosis of malignant blood diseases / 白血病·淋巴瘤
Journal of Leukemia & Lymphoma
;
(12): 416-418,422, 2012.
Article
in Chinese
| WPRIM
| ID: wpr-601807
ABSTRACT
Objective To study the clinical features bone marrow biopsy of secondary myelofibrosis(SMF).Methods 69 patients with secondary myelofibrosis were analyzed retrospectively,and the relationship between myelofibrosis degree and megakaryocyte count was analyzed. Results Analysis of 69 cases of patients with SMF, the original incidence included 20 cases (29.0 %)of chronic myeloid leukemia (CML),14 (20.3 %) cases of lymphoma,10 (14.5 %) cases of acute myeloid leukemia (AML),10 (14.5 %) cases of myelodysplastic syndrome (MDS),6 cases(8.7 %)of acute lymphoblastic leukemia (ALL),4 cases of multiple myeloma (MM),3 cases of myeloproliferative neoplasms (MPN),2 cases of chronic lymphocytic leukemia (CLL).There was no significant difference of the mygakaryocytes’ count and association of myelofibrosis with it was found (r=0.024,P=0.848). Conclusion Various clinical diseases of blood system may associated with secondary myelofibrosis. Bone marrow biopsy can be used to initial diagnostics of malignant disease of hematological system patients.When cellular examination of bone marrow is dry tap or dilution, which means higher incidence of SMF. Bone marrow biopsy plays an important role in diagnosis of SMF.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Leukemia & Lymphoma
Year:
2012
Type:
Article
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