The Impact of Intermittent Hypoxia from Obstructive Sleep Apnea on Cardiovascular and Cerebrovascular Diseases / 天津医药
Tianjin Medical Journal
;
(12): 946-948,949, 2014.
Article
in Chinese
| WPRIM
| ID: wpr-601926
ABSTRACT
Obstructive sleep apnea (OSA) is characterized by repeated intermittent hypoxia (IH), hypercapnia, sleep fragmentation and intrathoracic pressure change. IH is related to the clinical pathophysiological processes of hypertension, atherosclerosis, coronary heart disease, arrhythmia, stroke, heart failure and sudden death. IH from OSA can lead to metabol-ic dysregulation, endothelial dysfunction, systemic inflammation, oxidative stress and the change of nerve body fluids, which has been shown to increase the risk of cardiovascular diseases. This study mainly describes the pathogenesis of IH leading to the various cardiovascular diseases.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Tianjin Medical Journal
Year:
2014
Type:
Article
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