Study on relationship between helicobacter pylori infections and homocysteine / 重庆医学

ABSTRACT

Objective To explore the relationship between helicobacter pylori infections and homocysteine (Hcy) in health checkup population .Methods A total of 930 health checkup people in our hospital physical examination center during December 2012 to September 2013 were selected as the research object and were divided into Hp positive group (465 cases) and the negative group (465 cases) according to the Hp infection by the immune colloidal gold method .The level of Hcy was measured in two groups by fluorescence polarization immunoassay method .The relationship between helicobacter pylori infections and homocysteine was analyzed .Results The abnormal rate of high serum level of Hcy in Hp positive group was 68 .39% ,While 44 .30% in negative group ,the difference was statistically significant (P<0 .05);the abnormal rate of male was 88 .25% ,female 18 .80% ;the abnormal rate of male was 59 .76% ,and that of female was 5 .30% ,the difference of two groups had statistical significance (P<0 .05 ,P<0 .01) .Conclusion Hp infection may be a risk factor of high Hcy levels ,and taking measures actively to prevent and control Hp in‐fection may reduce the of the cardiovascular and cerebrovascular diseases .