Advances and enlightenment of myeloproliferative neoplasms associated gene mutations in thrombophilia and general population / 白血病·淋巴瘤
Journal of Leukemia & Lymphoma
;
(12): 412-414,419, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-602665
ABSTRACT
The detection of JAK2 V617F and CALR mutations,which was first reported in 2005 and 2013,respectively,had greatly improved the diagnosis and treatment of myeloproliferative neoplasms (MPN).Most MPN patients are inclined to thrombophilia,the carrier frequency of JAK2 V617F mutation was also high in patients of various thrombotic events,and the relationship between the two conditions needs further study.The observation of JAK2 V617F mutation in control group and general population also enlightened and changed the understanding about the development of chronic cancer.Research progress in this area will be introduced together with the related reports in the 56th American Society of Hematology annual meeting in 2014.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
Journal of Leukemia & Lymphoma
Year:
2015
Type:
Article
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