Observation of high-sensitivity C-reactive protein and white blood cell levels in patients with positive sputum culture results / 国际检验医学杂志

ABSTRACT

Objective To investigate the change of high‐sensitivity C‐reactive protein(hs‐CRP) and white blood cell(WBC) in patients with positive sputum culture results .Methods hs‐CRP and WBC were determined in 116 patients with positive sputum culture results ,which were divided into 5 groups according to strains ,and control group of patients with negative sputum culture re‐sults .Levels and abnormal rates of various parameters were compared between each group .Results hs‐CRP levels significantly in‐creased in the 5 sputum culture positive groups ,compared with control group(P<0 .05) ,and that of Candida albicans group was the most high .WBC and neutrophile granulocyte(NEU) levels of 4 positive groups were obviously raised(P<0 .05) besides Haemophi‐lus influenzae group ,and the elevation tendency was the most obvious in Streptococcus pneumoniae group .The 5 positive groups were all with high detectable rates of hs‐CRP elevation .The detectable rate of WBC elevation in Streptococcus pneumoniae group was 64 .7% ,higher than Haemophilus influenzae group(P<0 .05) .Conclusion The majority of patients with positive sputum cul‐ture results could be with inflammatory response because of bacterial infection or colonization .