Curative Effect of Polyene Phosphatidylcholine Injection Combined with Diammonium Glycyrrhizinate in the Treatment of Hyperthyroidism Liver Damage / 中国药师

ABSTRACT

Objective:To observe the curative effect of polyene phosphatidylcholine injection combined with diammonium glycyr-rhizinate in the treatment of liver damage in the patients with hyperthyroidism. Methods:Totally 45 cases of hyperthyroidism patients with impaired liver function were divided into two groups according to the order of admission and treated with anti-thyroid drugs in the conventional treatment. The control group was treated with diammonium glycyrrhizinate capsules 150 mg, po, tid, and the observation group was treated with polyene phosphatidylcholine injection 232. 5 mg, ivd, qd on the basis of the control group. After 30-day treat-ment, the clinical curative effect, changes in liver function and the incidence of adverse drug reactions of the two groups were observed and compared. Results:The total effective rate of the observation group was 95. 66%, which was significantly higher than that of the control group (63. 63%, P0. 05). No adverse drug reaction was shown in the observation group. Conclusion: Polyene phosphatidylcholine injection combined with diammonium glycyrrhizinate exhibits promising efficacy in the treatment of hyperthyroidism liver damage, which can significantly improve liver function in the patients with few adverse reactions and high safety, and is worthy of clinical promotion.