Retrospective Analysis on Serological Detection of Hepatitis Viruses in Physical Examination Population in Xi’an During 2009~2014 / 现代检验医学杂志

ABSTRACT

Objective To investigate retrospective analysis on serological detection of hepatitis viruses in physical examination population.Methods Hepatitis A virus (HAV)IgM,HBsAg,HCV IgG,HDV IgM,HEV IgM and HEV IgG were detected by ELISA assay in physical examination population during 2009~2014.Results The positive rate of HAV IgM was 0.15%(2/1 315)in 1 315 physical examinees and that of HBsAg was 2.83% (3 360/109 965)in 109 965 ones during 2009~2014. The positive rates of HBsAg decreased trend in the last 6 years in general (χ2 =63.070,P =0.001).There was no signifi-cant difference for HBsAg positive rate among male physical examinees in last six years (χ2 =4.804,P =0.441),but the positive rate of HBsAg in female population decreased trend in the last 6 years in general (χ2 =18.046,P =0.003),moreo-ver the positive rate of HBsAg in male popolation was significantly higher than that in female ones (χ2 =126.9,P =0.000). The positive rate of HCV IgG was 0.79% (333/41 898)in 41 898 physical examinees during 2009~2014 and that decreased trend in last 6 years (χ2 = 18.380,P =0.003).There was no HDV IgM detected in 1 079 physical examinees serum.The positive rate of HEV IgM and IgG were 0.25% (3/1 195)and 3.93% (47/1 195)respectively in 1 195 physical examinees. Conculsion The physical examination population during 2009~2014 were mainly infected by HBV and HCV and the infec-tion rate decreased trendly in last 6 years,which provided important data for epidemiology of serological hepatitis viruses in Shaanxi provice.