Correlation between expression of immune molecules of erythrocyte and T lymphocyte subsets in bone and joint tuberculosis patients in Western Guangxi / 重庆医学

ABSTRACT

Objective To investigate the changes of CD35 and CD59 of erythrocyte and T lymphocyte subsets and their sig-nificances in patients with bone and joint tuberculosis and pulmonary tuberculosis .Methods Venous blood was extracted from 60 bone and joint tuberculosis patients ,60 pulmonary tuberculosis patients ,and 90 healthy individuals(control group) .Flow cytometry (FCM ) was used to detect the concentration of T lymphocyte subsets ,such as CD3 + ,CD4 + ,CD8 + and CD4 + /CD8 + ,as well as im-mune molecules of erythrocyte ,such as CD35 and CD59 .Results CD3 + ,CD4 + ,CD4 + /CD8 + ,CD35 and CD59 in bone and joint tu-berculosis group and pulmonary tuberculosis group were significantly lower than those in control group(P 0 .05) .Conclusion Compared with the ordinary people ,there are significant differences be-tween erythrocyte and T lymphocyte immune in patients with bone and joint tuberculosis and pulmonary tuberculosis ,but it is the reason or the results need to be further studied .