Bacterial drug resistance surveillance in First Affiliated Hospital of Chongqing Medical University during 2014 / 国际检验医学杂志

ABSTRACT

Objective To investigate the resistance of clinically isolated bacteria to commonly used antibacterial drugs in the First Affiliated Hospital of Chongqing Medical University .Methods The bacterial susceptibility testing in clinically isolated bacte‐ria collected during January to December 2014 was carried out .The detection results were judged according to the standards by CLSI in 2014 .Results Among 7 740 clinical isolated strains of bacteria collected during this period ,Gram negative bacteria and Gram positive bacteria accounted for 70 .6% and 29 .4% respectively .Methicillin resistant(MR) strains in S .aureus and coagulase negative Staphylococcus accounted for 30 .2% and 77 .2% respectively .The resistance rates of MR strains to main antimicrobial a‐gents were much higher than those of methicillin sensitive(MS) strains .No staphylococcal strain was resistant to vancomycin or lin‐ezolid .The resistance rates of E .faecalis strains to main antibacterial agents was much lower than those of E .faecium .Some strains (2 .3% ) of E .faecium were found resistant to vancomycin ,while some strains(0 .9% ) of E .faecalis were found resistant to linezol‐id .The ESBLs producing strains were 59 .5% in Escherichia coli and 31 .8% in Klebsiella pneumoniae .Strains of Enterobacteriaceae were highly susceptible to imipenem and meropenem ,the overall resistance rates being less than 2 .0% .Resistance rates of P .aerug‐inosa to imipenem and meropenem were 24 .5% and 17 .9% ,respectively .The resistance rates of A .baumanii to the two carbapene‐ms were 71 .9% and 75 .0% ,respectively .The multi‐drug resistant K .pneumoniae and A .baumanii were increased markedly .Con‐clusion Bacterial drug resistance is serious ,especially the multi‐drug resistant bacteria constitute a serious threat to clinic .There‐fore it is urgent to strengthen the infection control measures .