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Determination of Anti-FIIαActivity in Compound Heparin Sodium Cream by a Trace Chromogenic Sub-strate Method / 中国药师
China Pharmacist ; (12): 1071-1072,1073, 2016.
Article in Zh | WPRIM | ID: wpr-604344
Responsible library: WPRO
ABSTRACT
Objective:To establish a trace chromogenic substrate method for the determination of anti-FIIαactivity in compound heparin sodium cream .Methods: The anti-FIIαactivity in compound heparin sodium cream was determined by a trace chromogenic substrate method according to the completely random design of experiment based on the amount reaction principle of 4*4 parallel lines in the biological test statistics method .Results:The calibration curve was linear within the range of 0.005 04 IU· ml-1-0.021 IU· ml-1(r=0.992).The average recovery was 101.6% with RSD of 2.76% (n=9).Conclusion: The method is accurate, reliable and reproducible , and can be used for evaluating the quality of compound heparin sodium cream .
Key words
Full text: 1 Index: WPRIM Language: Zh Journal: China Pharmacist Year: 2016 Type: Article
Full text: 1 Index: WPRIM Language: Zh Journal: China Pharmacist Year: 2016 Type: Article