Progress of diagnosis and treatment about syphilis infection causing infant cholestasis / 国际儿科学杂志

ABSTRACT

With the increasing rates of adult syphilis infection,some reports have suggested that the syphilis infection accounted for about 1.45％ of the etiology the infantile cholestasis,syphilis infection often lead to multiple organ and system dysfunction as a cause of infant cholestasis disease,it characterized by infantile cholestasis which performanced with jaundice,itchy skin,dark yellow urine,acholic stools,etc when it involved liver,syphilis infection can also merge with mucosal syphilis,osseous syphilis,neurosyphilis.The treatment of infant cholestasis caused by syphilis infection includes early system of adequate antisyphilitics treatment,meanwhile,we should cholagogue,removing jaundice,hepatic protection,and nutritional therapy for cholestasis.In this article,we are planing to review the etiology,clinical manifestation,diagnosis,treatment and prevention of the infantile cholestasis caused by syphilis infection.