Content Determination of Muscone in the Aiweixin Oral Liquid by GC-MS / 中国药房
China Pharmacy
;
(12): 2552-2553,2554, 2015.
Article
in Chinese
| WPRIM
| ID: wpr-605114
ABSTRACT
OBJECTIVE:
To establish a method for the content determination of muscone in Aiweixin oral liquid.METHODS:
After extracting sample by butanol,GC-MS was performed on the column of BD-17 MS with the volume temperature of 270 ℃;the carrier gas was helium with the sample size of 1 μl at the flow rate of 10 ml/min;the split ratio was 20∶1. EI was ion source with the electron energy of 70 eV,ion source temperature of 230 ℃ and quadrupole temperature of 150 ℃;the tuning mode was automatic tuning by quality full scanning with the threshold value of 30 in the range of 30-600 aum.RESULTS:
The linear range of muscone was 12.216-61.08 ng(r=0.999 6);RSD of precision test was lower than 2% and the RSDs of reproducibility and stability tests were lower than 3%;the average recovery was 100.24%(RSD=1.58%,n=6).CONCLUSIONS:
The method is sensitive, rapid and simple,and can be used for the content determination of muscone in Aiweixin oral lipid.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2015
Type:
Article
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