Efficacy Observation of Carboxymethyl Starch in the Treatment of Recurrent Respiratory Infection Chil-dren / 中国药房

ABSTRACT

OBJECTIVE:To observe clinical efficacy of carboxymethyl starch in the treatment of recurrent respiratory infection (RRI)children. METHODS:110 RRI children were selected and randomly divided into observation group and control group,with 55 children in each group. Control group was given routine treatment,such as anti-infection,anti-virus,abatement of fever,reliev-ing cough,phlegm transformation and etc. Observation group was additionally given Carboxymethyl starch sodium solution (7 ml for 7 year-old)on the basis of control group. Both groups received consecutive treatment for 3 months. The changes of cellular immunity function index CD4+,CD8+ and CD4+/CD8+ and humoral immunity index IgG,IgA and IgM were observed in 2 groups before and after treatment,and clinical efficacy was evaluated in 2 groups. RE-SULTSThere was no statistical significance in CD4+,CD8+and CD4+/CD8+levels of control group before and after treatment(P>0.05);after treatment,CD4+ and CD4+/CD8+ of observation group obviously increased,while CD8+ level obviously declined;the observation group was better than control group,with statistical significance (P0.05);after treatment,IgG,IgA and IgM levels of control group increased significantly,and the observation group was better than control group,with statistical significance (P<0.05). Total effective rate of observation group was 92.73%,which was much higher than that in control group (78.18%),with statistical significance(P<0.05). CONCLUSIONS:Carboxymethyl starch has definite therapeutic efficacy on RRI,and can obvi-ously improve cellular and humoral immunity function.