Determination of Trace Platinum in Zolpidem Tartrate by GFAAS / 中国药房
China Pharmacy
;
(12): 838-839,840, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-605263
ABSTRACT
OBJECTIVE:
To establish a method for determination of trace platinum in zolpidem tartrate.METHODS:
Graphite furnace atomic absorption spectrometry(GFAAS)was adopted for direct determination after dissolving sample in 1% Hydrochloric acid solution. Horizontal platform graphite tube was performed with detection wavelength of 244.79 nm,slit width of 0.2 nm and current intensity of hollow cathode lamp of 6 mA. The mode of background correction was zeeman effect,the peak height was used as measurement pattern,and the injection volume was 20 μl.RESULTS:
The linear range of platinum was 0-100 ng/ml(r=0.999 0);RSDs of precision and reproducibility tests were no more than 2.0%;recovery was 97.78%-103.07%(RSD=1.6%,n=9);the detection limit was 1.48 ng/ml.CONCLUSIONS:
This method is simple and rapid with good precision and accuracy,and can be applied for the determination of trace platinum in zolpidem tartrate.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2016
Type:
Article
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