Study on Water Extraction Process of Traditional Chinese Medicine Qubai Granule by Orthogonal Test / 中国药师

ABSTRACT

Objective:To optimize the water extraction process of traditional Chinese medicine ( TMC) Qubai granule. Methods:The orthogonal test was used to study four influencing factors including water amount, soaking time, extraction time and extraction times with dry extract yielding rate and the content of ferulic acid as the evaluation indices. Results:The optimum extraction process was as followsA2 B1 C2 D2 , namely adding 10-fold amount of water, without soaking in advance, extracting twice with 2 h for each time. Con-clusionThe process is simple, stable and reproducible, which provides basis for the industrial production.