Rapid Contents Determination of Potassium Chloride and Calcium Chloride in Compound Sodium Chloride Injection by ICP-OES / 中国药房
China Pharmacy
;
(12): 2538-2539,2540, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-605735
ABSTRACT
OBJECTIVE:
To establish a method for the rapid contents determination of potassium chloride and calcium chloride in Compound sodium chloride injection.METHODS:
After diluted in appropriate way,Compound sodium chloride injection was sampled directly and contents of potassium chloride and calcium chloride were determined simultaneously by ICP-OES. The powder was 1 300 W,plasma gas flow rate was 15 L/min,auxiliary cooling gas flow was 0.2 L/min,atomizer flow rate was 0.8 L/min, the peristaltic pump rate was 0.8 L/min,atomizer pressure was 315 kPa,and the observation was axial observation,analysis spec-tral lines of potassium and calcium were 766.490 nm and 315.887 nm.RESULTS:
The linear ranges of potassium and calcium were 1.0-12.0 mg/L (r=0.999 7 and 0.999 9);RSDs of precision and reproducibility tests were lower than 1%;recoveries were 98.5%-100.5%(RSD=0.59%,n=9)and 99.3%-102.3%(RSD=0.98%,n=9).CONCLUSIONS:
The method is simple,rapid and simple,and can be used for the quality control of Compound sodium chloride injection.
Full text:
Available
Index:
WPRIM (Western Pacific)
Language:
Chinese
Journal:
China Pharmacy
Year:
2016
Type:
Article
Similar
MEDLINE
...
LILACS
LIS