Impact of Renal Function Injury on the Diagnostic Value of NT-proBNP in Patients With Heart Failure / 中国循环杂志
Chinese Circulation Journal
;
(12): 1189-1192,1193, 2016.
Article
in Chinese
| WPRIM
| ID: wpr-605981
ABSTRACT
Objective:
To explore the impact of renal function injury on diagnostic value of NT-proBNP in patients with heart failure (HF).Methods:
A total of 420 patients with cardiovascular disease at (50-75) years of age were divided into 2 groups based on left ventricular ejection fraction (LVEF) Control group, the patients with normal cardiac function, LVEF≥40%,n=232 and HF group, LVEFeGFR≥60 ml/min·1.73m2), Moderate renal injury (60>eGFR≥30 ml/min·1.73m2) and Severe renal injury (eGFRResults:
Compared with Control group, HF group had increased blood level of NT-proBNP,P0.05, while it was much higher in Moderate and Severe renal injury subgroups than Normal renal function subgroup,PConclusion:
Moderate to severe renal function injury could increase circulating level of NT-proBNP and therefore, the cut-off value of NT-proBNP for HF diagnosis should be elevated accordingly in patients of HF combing renal injury.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
Language:
Chinese
Journal:
Chinese Circulation Journal
Year:
2016
Type:
Article
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