Forewarning value of AFP and GP7 3 detection in canceration of patients with liver cirrhosis / 国际检验医学杂志

ABSTRACT

Objective To evaluate the forewarning value of alpha-fetoprotein (AFP)and golgi protein73(GP73)in canceration of the patients with liver cirrhosis.Methods The levels of AFP and GP73 were respectively tested by chemiluminescence immuno-assay and ELISA.Fifty patients with liver cirrhosis were performed 24-month follow up for understanding the liver cancer occur-rence situation.The value of AFP and GP73 for predicting the liver cancer occurrence risk in the patients with liver cirrhosis was analyzed and compared.Results The canceration rate after 18,24 months follow up in the liver cirrhosis patients with GPP(+) was significantly higher than that with AFP(+),the difference was statistically significant(P>0.05).Conclusion AFP and GP-73 all have the predictive value for canceration of liver cirrhosis,moreover GP73 has more forewarning value.