Trend and epidemiological analysis of congenital heart disease / 心血管康复医学杂志

ABSTRACT

Objective:To explore trend of congenital heart disease (CHD) ,analyze its epidemiological features and risk factors .Methods:A total of 2415 children diagnosed as CHD in our hospital from Jan 2012 to Jan 2015 were en‐rolled as CHD group ,another .Detection rate of every year ,constitution type and constituent ratio of each age group for CHD were counted .Multifactor Logistic regression analysis was used to analyze independent risk factors and protective factors of CHD .Results:CHD detection rate of 2012 ,2013 and 2014 was 19.42% ,34.99% and 45.59% respectively ,showing an increasing trend (P=0.018 ,0.107) .The top three types of CHD were atrial sep‐tal defect (ASD , 37.31% ) , ventricular septal defect (VSD , 30.97% ) and patent ductus arteriosus (PDA , 13.71% ) .Comparison among all age groups found that 1 year children ;< 4 years CHD children occupied 74. 95% for all CHD children .Multifactor Logistic regression analysis indicated that educa‐tion level of mother was independent protective factor for CHD [OR=0.488 ,P=0.011] ,threatened abortion his‐tory ,smoking history of father and interior renovation during pregnancy were independent risk factors for CHD [OR=1.748~7.151 ,P<0.05 or <0.01] .Conclusion:Detection rate of congenital heart disease shows a gradual increasing trend in recent years ,periodic inspection and early intervention focus on parents status and environmental factors must be performed in order to achieve goals of early diagnosis ,prevention and treatment .