Chest CT Features of Oral Paraquat-induced Lung Injury / 中国医学影像学杂志

ABSTRACT

Purpose To investigate the chest CT features of lung injury caused by oral paraquat,and deepen the understanding of paraquat poisoning.Materials and Methods The chest CT features of 74 patients with lung injury caused by oral paraquat were analyzed retrospectively and comparatively.74 patients were divided into 3 groups according to toxic dose28 cases in the low dose group (paraquat dose less than 10 ml),34 cases in the medium dose group (paraquat dose among 11 to 50 ml),and 12 cases in the large dose group (paraquat dose more than 50 ml).74 patients were also divided into 3 groups according to course of diseaseThe course of disease among 1 to 7 days were in the early period,8 to 14 days in the medium period,and 14 days later in the later period.The image features were summarized by comparing the chest CT features,with toxic dose,course of disease,and the scope of lung injury.Results Poisoned patient's chest CT features,related with toxic dose (P＜0.05),appeared from increased bronchovascular shadows,ground glass opacity,to effusion and consolidation,and to pulmonary fibrosis along with time.The effusion and consolidation majorly located in the lateral lungs,which showed a characteristic disease extent.Conclusion The chest CT features of lung injury,caused by oral paraquat,have a certain characteristic.It relates to toxic dose and course of disease,which has a certain guiding significance to clinical diagnosis and treatment.