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Clinical observation of different wavelength laser in the treatment of severe non-proliferative diabetic retinopathy / 眼科新进展
Recent Advances in Ophthalmology ; (6): 842-845, 2017.
Article in Chinese | WPRIM | ID: wpr-607210
ABSTRACT
Objective To compare the clinical effects of 577 nm and 532 nm laser panretinal photocoagulation in the treatment of severe non-proliferative diabetic retinopathy (NPDR).Methods A prospective,controlled trial was conducted in 42 patients(64 eyes)with severe NPDR,who were randomly divided into 577 nm group and 532 nm group.All of patients received PRP with the single-point model.Preoperative and postoperative 1 day,1 month,3 and 6 months,the best corrected visual acuity (BCVA),fundus,optical coherence tomography (OCT) and full field flash electroretinogram (F-ERG) were examined.After treatment 3 and 6 months,fundus fluorescein angiography (FFA) examination was performed between two groups.Results In 577 nm group and 532 nm group,the average number of laser spot was (1969.25 ± 278.19) and (2098.16 ± 289.27) respectively;average laser power was (425.23 ± 50.15)mW and (438.15 ± 38.48)mW respectively;and average energy density was (7.54 ± 1.54) mW · ms · μm-2 and (7.68 ± 3.01)mW · ms · μm-2.There was no difference in number of laser spot(t =2.68),laser power (t =1.46) and energy density (t =2.15) between the two groups (all P > 0.05),and the differences of macular central thickness after treatment 1 month,3 and 6 months (t =1.98,1.88,1.81 respectively) approached no statistical significance between the two groups (all P > 0.05),while F-ERG a,b wave amplitudes after treatment 1 month,3 and 6 months (a wavet =5.94,5.19,6.97;b wavet =5.67,4.56,5.12) had significant differences between groups (all P < 0.05).The effective rate of treating 6 months after operation in the two groups were 87.5% and 46.9% respectively,with significant difference (x2 =7.56,P < 0.05).Conclusion 577 nm laser is more effective and has less damage to visual function than 532 nm laser in the treatment of NPDR.

Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Recent Advances in Ophthalmology Year: 2017 Type: Article

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Full text: Available Index: WPRIM (Western Pacific) Language: Chinese Journal: Recent Advances in Ophthalmology Year: 2017 Type: Article