The Safety Assessment of Percutaneous Transhepatic Transpapillary Stent Insertion in Malignant Obstructive Jaundice: Regarding the Risk of Pancreatitis and the Effect of Preliminary Endoscopic Sphincterotomy / 대한소화기학회지
The Korean Journal of Gastroenterology
;
: 390-394, 2009.
Article
in Korean
| WPRIM
| ID: wpr-60798
ABSTRACT
BACKGROUND/AIMS:
Metal stent insertion through percutaneous transhepatic biliary drainage (PTBD) track is an important palliative treatment modality for malignant biliary obstruction. Acute pancreatitis is one of serious complications of biliary metal stenting. The purpose of this study was to investigate the risk of pancreatitis for patients who underwent metal stent insertion via PTBD track.METHODS:
A retrospective analysis of 90 consecutive patients who received metal stent insertion via PTBD track from Jan. 2002 to Dec. 2007 was carried out. Patients were devided into the transpapillary and non-transpapillary group, and the risks of pancreatitis were compared. The effects of preliminary endoscopic sphincterectomy (EST) was also investigated in transpapillary group.RESULTS:
The rate of pancreatitis was higher in transpapillary group compared to nontranspapillary group (odd ratio 1.87, 95% CI 0.516-6.761), but it showed no stastically significance (p=0.502). In transpapillary group, patients who received preliminary EST showed lower rate of pancreatitis (odd ratio 0.91, 95% CI 0.656-1.273), but it showed no stastically significance (p=0.614).CONCLUSIONS:
Metallic stent insertion through the intact sphincter of Oddi might have a risk of developing pancreatitis. Further study is needed to elucidate the mechanism of pancreatitis and the way of prevention.
Full text:
Available
Index:
WPRIM (Western Pacific)
Main subject:
Pancreatitis
/
Stents
/
Drainage
/
Cholestasis
/
Retrospective Studies
/
Sphincterotomy, Endoscopic
/
Risk Assessment
/
Jaundice, Obstructive
/
Amylases
Type of study:
Etiology study
/
Observational study
/
Risk factors
Limits:
Aged
/
Aged80
/
Female
/
Humans
/
Male
Language:
Korean
Journal:
The Korean Journal of Gastroenterology
Year:
2009
Type:
Article
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