Study on Signal Detection of Xiyanping Injection-induced Urticaria Based on BCPNN Warning Technology / 中国药房
China Pharmacy
;
(12): 1921-1924, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-607985
ABSTRACT
OBJECTIVE:
To explore and analyze signals of Xiyanping injection-induced urticaria from spontaneous reporting system database of Jiangxi province.METHODS:
The continuous ADR report monitoring data were collected from spontaneous re-porting system of Jiangxi province,and established database. Bayesian confidence propagation neural network(BCPNN) method was used to calculate information component,IC value of Xiyanping injection-induced urticaria. The year-to-year changes of IC val-ue and its interval were analyzed.RESULTS:
A total of 328324 ADR reports were collected in Jiangxi province during 2004-2016. The IC value of Xiyanping injection-induced urticaria detected by BCPNN method was 1.10(the lower limit of IC value was 0.65, and upper limit was 1.54),i.e. there was signal and the IC value ranged from-0.87 to 1.65.CONCLUSIONS:
The results of BCPNN method suggest that urticaria is a warning signal of Xiyanping injection. The risk is increasing gradually,and prediction precision increase with the addition of report quantity.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Diagnostic study
/
Prognostic study
Language:
Chinese
Journal:
China Pharmacy
Year:
2017
Type:
Article
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