Level of pulmonary surfactant protein D and human type Ⅰ protein in bronchoalveolar lavage fluid and serum in children with mycoplasma pneumoniae pneumonia / 国际儿科学杂志
International Journal of Pediatrics
;
(6): 291-293, 2017.
Article
in Chinese
| WPRIM
| ID: wpr-608603
ABSTRACT
Objective To evaluate the levels of pulmonary surfactant protein D (SP-D) and 56-kD human type Ⅰ protein(HTI-56) in bronchoalveolar lavage fluid and serum of children with mycoplasma pneumoniae pneumonia,as well as their potential as biomarkers of mycoplasma pneumoniae pneumonia.Methods A retrospective study was conducted in 57 children with mycoplasma pneumoniae pneumonia from June 2011 to June 2016 in our hospital.In this study,the levels of SP-D and HTI-56 in bronchoalveolar lavage fluid and serum were determined and compared between unilateral lung infection and bilateral lung infection.Results SP-D and HTI-56 levels were significantly higher in bronchoalveolar lavage fluid samples (P < 0.05)compared with bronchoalveolar lavage fluid samples from uninfected lungs (P < 0.05).However,the serum levels of SP-D and HTI-56 in children with unilateral lung infection and bilateral pulmonary infection were not significantly different (P >0.05).Conclusion High levels of SP-D and HTI-56 in bronchoalveolar lavage fluid samples from infected lungs may reflect damage to alveolar epithelial cells caused by mycoplasma pneumoniae.
Full text:
Available
Index:
WPRIM (Western Pacific)
Type of study:
Observational study
Language:
Chinese
Journal:
International Journal of Pediatrics
Year:
2017
Type:
Article
Similar
MEDLINE
...
LILACS
LIS