Three-dimensional speckle tracking imaging technology in evaluation on systolic function of left ventricular in patients with preeclampsia / 中国医学影像技术

ABSTRACT

Objective To evaluate the systolic function in patients with preeclampsia using three-dimensional speckle tracking imaging (3D-STI) technology.Methods Totally 73 patients with mild preeclampsia (mild group),64 patients with severe preeclampsia (severe group) and 60 healthy pregnant women with matched age and gestational weeks (control group) were enrolled in this study.All the biochemical indicators and conventional echocardiogram parameters were detected.The left ventricular global longitudinal systolic peak strain (GLS),global radial systolic peak strain (GRS),global circulation systolic peak strain (GCS) and global area systolic peak strain (GAS) were measured using 3D-STI,and the dyssynchronization index of area strain (ASDI) was calculated in all three groups.The correlation between sensitive three dimensional strain and biochemical indexes and echocardiogram parameters were analyzed.Results Compared with control group,the left atrial diameter (LAD) increased,E/A decreased in severe group,Tei index increased in turn at control group,mild group and severe group (all P＜0.05).Compared with control group,the |GLS| and |GAS| reduced and ASDI was increased in mild group,the changes were more significant in severe group.The GRS and GCS were also appeared lower in severe group (all P＜0.05).The correlation analysis showed a negative correlation between |GLS| and Tei index (r=-0.471,P=0.036),a positive correlation between | GAS| and LVEF (r=0.051,P=0.028),a negative correlation between | GAS| and Tei index (r=-0.612,P =0.017),a negative correlation between ASDI and H-FABP (r=-0.525,P=0.046),a positive correlation between ASDI and Tei index (r=0.489,P=0.037).Conclusion The myocardial strain capacity of left ventricular decrease and systolic function are significantly impaired in patients with preeclampsia.The 3D-STI technology can early noninvasively assess the change of left ventricular systolic function in patients with preeclampsia.