Hypotensive Efficacy and Safety of Ramipril on the Patients with Essential Hypertension
Korean Circulation Journal
; : 774-780, 1991.
Article
in Ko
| WPRIM
| ID: wpr-60894
Responsible library:
WPRO
ABSTRACT
Thirty three patients with mild to moderate essential hypertension were administered ramipril, a new ACe inhibitor, 2.5-5mg once daily for 6 weeks to evaluate the hypotensive efficacy and safety. The results were as follows : 1) The patients consisted of 18 males, 15 females, aged 54 on average and classified as mild in 19 and moderate in 14 patients. 2) At the end of 6 weeks trial, blood pressure dropped 13/6mmHg on average, rewarding 70% effectiveness and normalized below 150/90mmHg in 39%. 3) The most frequent side reaction was dry cough in 5 patients(15%) followed by asthenia, GI trouble, dizziness, edema, eye injection and one case of GPT elevation which normalized after completion of trial. 4) The rating of safety of safety was 79% and of overall usefulness was 73%. In conclusion, ramipril 5mg once daily regimen is well tolerated and effective in the treatment of mild to moderated essential hypertension.
Key words
Full text:
1
Index:
WPRIM
Main subject:
Asthenia
/
Reward
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Blood Pressure
/
Ramipril
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Cough
/
Dizziness
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Edema
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Hypertension
Limits:
Female
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Humans
/
Male
Language:
Ko
Journal:
Korean Circulation Journal
Year:
1991
Type:
Article