Comparison of pregnancy outcome of blastocyst cryopreserved with different carrier in thawed-frozen embryo transfer cycle / 中国医师杂志

ABSTRACT

Objective To compare the pregnancy outcome of blastocyst which were cryopreserved in different carrier:cryotop and cryoLogic vitrification method (CVM) embryo freezing carriers.Methods Data were collected retrospectively from January 2014 to August 2015.All the thawed-frozen embryo transfer (FET) cycles were the first one after their fresh embryo transfer.According to the freezing carrier,they were divided into two groups:Cryotop group (n =114) and CVM group (n =232).The pregnancy outcome in FET cycles was compared between two groups.Results The clinical pregnancy rate,implantation rate,and the birth rate were significantly higher in group cryotop.The recovery rate,the rate of multiple births,ectopic pregnancy,miscarriage,premature birth rate,birth weight,and birth defect rate were similar in two groups.Conclusions Compared to CVM frozen carrier,the thawed-frozen embryo cyropreserved in Cryotop has higher clinical pregnancy rate,higher implantation rate,and live birth rate.