Relationship between central lymph node metastasis and clinical features of papillary thyroid microcarcinoma / 肿瘤研究与临床

ABSTRACT

Objective To analyze the relationship between central lymph node metastasis and clinical features of papillary thyroid microcarcinoma. Methods From January 2010 to October 2016, 137 patients were treated with papillary thyroid microcarcinoma and central lymph node dissection. Among them, 35 were male and 102 were female. There were 49 cases with age ≤ 45 years old, 88 cases > 45 years old. 36 cases had diameter of tumor≤5 mm, 101 cases>5 mm; There were 72 cases with tumor fibrosis, 65 cases without fibrosis; 22 cases with psammoma bodies, 115 cases without psammoma bodies. There were 16 cases with tumor associated with chronic lymphocytic thyroiditis, 121 cases without them. The clinical factors affecting lymph node metastasis in the central group were analyzed byχ2 test. Results Of the 137 patients, 52 cases (38.0%) had central lymph node metastasis. Age, tumor diameter, fibrosis, psammoma bodies had relationship with central lymph node metastasis (χ2 values were 4.48, 5.60, 7.30, 7.30, all P 0.05). Conclusion The papillary thyroid microcarcinoma patients with age≤45 years old, tumor diameter>5 mm, fibrosis in the tumor area and psammoma bodies have high risk of lymph node metastasis.