Contrast-enhanced Ultrasound Guided Percutaneous Puncture Injecting for Hemostatic Control of Active Bleeding of Closed Renal Trauma: An Experimental Study / 中国医学影像学杂志

ABSTRACT

Purpose Contrast-enhanced ultrasound (CEUS) guided percutaneous puncture injection of hemostatic agents or biological glue is good for the control of closed renal trauma,but there are also some shortcomings.This study aims to explore the effect of CEUS guided percutaneous puncture injection of hemostatic agent and xanthan gum on the control of closed renal trauma hemorrhage.Materials and Methods Sixteen healthy white rabbits were established closed renal trauma models of active bleeding,and were randomly divided into two groups,puncture and laparotomy group.The puncture group was treated with CEUS guided percutaneous injection of snake venom enzyme and biological glue into the active renal hemorrhage.The laparotomy group was treated with traditional surgical suture.The therapeutic effect of two groups was evaluated after operation.The treatment time was recorded,and the renal function was measured every week after the operation.The pathological examination of the wound tissue was performed 1 month after operation.Results Two groups were successful hemostasis.The operation time of puncture group and open group was (179 ± 30) s and (298 ± 30) s,respectively,and the difference was statistically significant (P＜0.05).After operation,the serum creatinine of the puncture group was lower than that of the laparotomy group,and the difference was statistically significant (P＜0.05).The recovery of renal function of the puncture group was faster than that of the laparotomy group,and the renal wound healing was better than that of the laparotomy group.Conclusion The effect of CEUS guided percutaneous puncture injection of snake venom enzyme combined with biological glue in the treatment of closed renal trauma hemorrhage is good,which is a new method worth recommending for easy operation,small damage and quick recovery.